Table 4.

OR of lung cancer for serum cotinine level stratified by sex and attained age

Serum cotinine level* (ng/mL)N casesN controlsOR (95% CI)N casesN controlsOR (95% CI)
SexWomenMen
0.1-5.0 (reference)472071.00885481.00
5.1-114.725751.54 (0.65-3.69)471721.83 (1.02-3.30)
114.8-223.8724811.9 (5.56-25.3)20319810.5 (6.59-16.6)
223.9-317.71244823.1 (11.0-48.3)38519927.8 (17.7-43.8)
>317.71514147.2 (21.3-105)59920542.1 (27.1-65.3)
Attained age≤60 y>60 y
0.1-5.0 (reference)593881.00693451.00
5.1-114.7301161.60 (0.73-3.51)391031.96 (1.01-3.78)
114.8-223.811811013.1 (7.17-24.1)15012310.1 (5.85-17.3)
223.9-317.724812129.9 (16.7-53.5)23811525.3 (14.6-43.9)
>317.739310360.0 (33.6-107)31811833.7 (19.6-57.9)
  • NOTE: OR is based on conditional logistic regression analysis, adjusting for year of birth, time of enrollment, geographical region, and in the analysis of attained age and sex.

  • * Categories are based on serum cotinine level only, not on self-reported smoking status.