Table 1.

Baseline demographic, clinical, and serum adipokines concentrations, cases versus controls, and high-grade versus low-grade disease from the SABOR cohort

Cases (n = 125)Controls (n = 125)PHigh grade (n = 40)Low grade (n = 85)P
Mean age ± SD (y)63.5 ± 7.463.2 ± 7.6Matched61.8 ± 7.163.7 ± 7.70.07
Race/ethnicity (%)
    Non-Hispanic Caucasian56.869.156.356.10.86
    Hispanic Caucasian26.419.127.624.4
    African American16.811.80.1416.119.5
Family history
    Yes30.426.035.926.2
    No69.674.00.4364.1073.80.27
BMI (%)
    Normal (<25 kg/m2)16.917.518.415.00.88
    Overweight (25-29.9 kg/m2)50.038.149.450.0
    Obese (≥30 kg/m2)33.144.40.1232.235.0
Mean BMI ± SD (kg/m2)28.4 ± 4.129.4 ± 4.90.0828.5 ± 4.528.1 ± 3.90.07
Mean waist circumference ± SD (cm)101.8 ± 12.7103.9 ± 12.60.08102.1 ± 12.2100.4 ± 12.90.07
Serum adiponectin (μg/mL)
    Mean ± SD17.9 ± 10.619.9 ± 13.20.2019.8 ± 12.417.1 ± 4.40.19
    Median (interquartile range)15.9 (11.4-22.1)15.84 (12.2-26.4)0.2715.9 (12.4-23.2)15.9 (11.0-20.0)
Serum leptin (pg/mL)
    Mean ± SD8.62 ± 7.411.1 ± 11.70.099.6 ± 9.48.2 ± 6.20.32
    Median (interquartile range)6.3 (3.2-12.6)7.6 (4.2, 14.3)0.116.6 (1.9-14.9)5.9 (3.3-12.3)0.34
Serum IL-6 (pg/mL)
    Mean ± SD70.9 ± 128.6107.8 ± 180.50.0746.2 ± 62.982.5 ± 68.70.06
    Median (interquartile range)14.5 (1.5-182.7)19.6 (3.3-106.5)0.1115.4 (3.7-52.6)12.1 (1.2-113.8)0.09