Table 5.

Association of selected four-locus XRCC4 haplotypes and age at diagnosis of breast cancer

Haplotype* (code)Mean statisticPMean ± SD age at diagnosis (range)
A-G-T-T (H1)0.290.78556.00 ± 12.87 (27-86)
A-G-T-G (H5)3.610.00167.17 ± 10.94 (49-84)
A-G-C-T (H6)0.220.83756.83 ± 15.58 (32-86)
A-G-C-G (H10)0.620.56257.14 ± 11.23 (39-81)
G-A-T-T (H2)−2.660.008554.04 ± 11.58 (29-81)
G-A-T-G (H7)1.260.24861.43 ± 11.79 (45-74)
  • * Carriage of each phased haplotype composed of tSNPs X1-X2-X3-X4 was compared with all other diploid combination of haplotypes.