Table 3.

Estradiol (E2) levels at baseline and after 12 months on raloxifene

Serum E2 levels (pg/mL)Baseline, mean ± SD12 mos on raloxifene, mean ± SDMean change from 0 to 12 mos ± SDP*95% CI for mean change
All subjects (n = 20)102 ± 67150 ± 10248 ± 900.036-90
Subjects with both E2 measurements at days 3-9 of menstrual cycle (n = 15)87 ± 50129 ± 10142 ± 740.0481-84
Subjects with baseline E2 measurement at day 10 or 11 of menstrual cycle (n = 2)240 ± 71182 ± 83−59 ± 12NANA
Subjects with 12-mo E2 measurement at day 10 or 11 of menstrual cycle (n = 3)85 ± 43234 ± 99149 ± 103NANA
  • Abbreviation: NA, not applicable.

  • * Based on Wilcoxon signed rank analysis.

  • Twelve-month measurement at days 3 to 9 of menstrual cycle.

  • Baseline measurement at days 3 to 9 of menstrual cycle.