Table 2.

hrHPV type distribution and cumulative 18-month risks of ≥CIN2 and ≥CIN3 in women with an hrHPV-positive BMD smear

hrHPV type at baselineAt risk
CIN2
CIN3
ACIS
SCC
AdCa
≥CIN2
≥CIN3
NRisk, % (95% CI)PRisk, % (95% CI)P
Single + multiple hrHPV infections
    Any374455713234 (29-39)20 (16-25)
    1612412343148 (38-58)0.000637 (28-48)<0.0001
    HPV16-positive cases excluded
        Any25033231127 (21-33)12 (8-17)
        1838621129 (15-47)0.61011 (3-27)0.883
        31485937 (23-54)0.21927 (14-46)0.016
        33246549 (29-71)0.00122 (9-44)0.025
        35221110 (0-33)0.0645 (0-32)0.282
        39292319 (7-39)0.44411 (3-30)0.842
        4527118 (0-29)0.0674 (0-26)0.229
        51397430 (17-47)0.68713 (4-30)0.830
        52224125 (10-50)0.9445 (0-30)0.285
        56282215 (7-36)0.1897 (0-27)0.507
        5819634 (16-61)0.4520 (0-28)0.122
        594150 (0-81)0.72550 (0-81)0.115
        66201113 (0-41)0.1846 (0-36)0.526
        689236 (3-60)0.8730 (0-34)0.545
Single hrHPV infections only
    Any282324313234 (28-40)21 (16-27)
    16956263146 (35-58)0.00939 (29-51)<0.0001
    HPV16-positive cases excluded
        Any18726171128 (21-36)12 (8-18)
        181541143 (20-73)0.28613 (7-53)0.871
        31344844 (26-64)0.08934 (16-57)0.005
        33164350 (23-76)0.01521 (6-52)0.226
        35101120 (10-70)0.58910 (0-70)0.739
        3912110 (0-57)0.27310 (0-57)0.940
        45161113 (0-47)0.3587 (0-43)0.481
        51224124 (10-50)0.6295 (0-32)0.340
        52141116 (0-50)0.3568 (0-46)0.647
        56171113 (0-44)0.2286 (0-40)0.451
        5812546 (17-80)0.1220 (0-26)0.285
        5920 (0-84)0.5420 (0-84)0.655
        66100 (0-31)0.0950 (0-31)0.346
        687133 (0-58)0.8460 (0-41)0.590