Cell cycle markers in high-risk HPV-positive and high-risk HPV-negative lesions
| Marker | HCII positive, OR (95% CI) | HCII negative, OR (95% CI) | Significance* |
|---|---|---|---|
| MI† | 2.87 (2.10-3.64) | 2.81 (0.05-5.68) | 0.959 |
| AI‡ | 1.82 (1.43-2.22) | 1.62 (0.13-3.11) | 0.743 |
| Ki-67§ | 14.04 (11.27-16.80) | 10.40 (3.80-16.99) | 0.303 |
| p21§ | 12.40 (8.88-15.91) | 9.80 (4.40-15.19) | 0.525 |
| Cyclin A§ | 19.88 (16.18-23.59) | 6.78 (3.80-9.77) | 0.002 |
| E2F4§ | 0.49 (0.26-0.72) | 0.68 (0.40-1.76) | 0.609 |
| p105§ | 42.98 (35.50-50.46) | 35.00 (21.51-48.48) | 0.351 |
| p107§ | 12.72 (9.40-16.05) | 11.31 (6.34-16.28) | 0.705 |
| p130§ | 40.12 (31.08-49.17) | 22.35 (3.50-41.20) | 0.085 |