Cases | RR (95% CI) | |||||
---|---|---|---|---|---|---|

Unadjusted | Adjusted* | |||||

Height (cm)^{†} | ||||||

Q1 | 42 | 1.00 | 1.00 | |||

Q2 | 72 | 1.63 | 1.63 (1.10-2.41) | |||

Q3 | 62 | 1.46 | 1.45 (0.96-2.20) | |||

Q4 | 60 | 1.78 | 1.78 (1.16-2.73) | |||

Per 10 cm | 1.37 | 1.38 (1.12-1.70) | ||||

P_{trend} = 0.003 | ||||||

P_{heterogeneity} = 0.30 | ||||||

Weight (kg)^{‡} | ||||||

Q1 | 49 | 1.00 | 1.00 | |||

Q2 | 48 | 1.03 | 1.07 (0.71-1.61) | |||

Q3 | 62 | 1.13 | 1.10 (0.75-1.60) | |||

Q4 | 77 | 1.35 | 1.27 (0.87-1.83) | |||

Per 5 kg | 1.07 | 1.06 (1.00-1.12) | ||||

P_{trend} = 0.03 | ||||||

P_{heterogeneity} = 0.70 | ||||||

BMI (kg/m^{2}) | ||||||

<20 | 6 | 0.59 | 0.55 (0.23-1.31) | |||

20-22.9 | 39 | 1.00 | 1.00 | |||

23-24.9 | 61 | 0.85 | 0.87 (0.58-1.31) | |||

25-26.9 | 51 | 0.71 | 0.74 (0.49-1.14) | |||

27-29.9 | 33 | 0.72 | 0.75 (0.46-1.24) | |||

30-34.9 | 36 | 1.07 | 1.10 (0.69-1.76) | |||

35+ | 6 | 1.20 | 1.22 (0.60-2.49) | |||

Per 5 kg/m^{2} | 1.12 | 1.14 (0.97-1.33) | ||||

P_{trend} = 0.11 | ||||||

P_{heterogeneity} = 0.34 | ||||||

Hip circumference^{§} (cm) | ||||||

Q1 | 48 | 1.00 | 1.00 | |||

Q2 | 43 | 0.88 | 0.88 (0.58-1.34) | |||

Q3 | 48 | 0.98 | 0.96 (0.64-1.46) | |||

Q4 | 66 | 1.35 | 1.31 (0.88-1.94) | |||

Per 10 cm | 1.16 | 1.15 (0.97-1.36) | ||||

P_{trend} = 0.10 | ||||||

P_{heterogeneity} = 0.61 | ||||||

Waist circumference^{∥} (cm) | ||||||

Q1 | 36 | 1.00 | 1.00 | |||

Q2 | 42 | 0.90 | 0.89 (0.57-1.39) | |||

Q3 | 58 | 1.17 | 1.13 (0.74-1.72) | |||

Q4 | 69 | 1.39 | 1.29 (0.85-1.97) | |||

Per 10 cm | 1.24 | 1.21 (1.07-1.37) | ||||

P_{trend} = 0.003 | ||||||

P_{heterogeneity} = 0.20 | ||||||

Waist-to-hip ratio^{¶} | ||||||

Q1 | 30 | 1.00 | 1.00 | |||

Q2 | 46 | 1.11 | 1.10 (0.69-1.75) | |||

Q3 | 50 | 1.11 | 1.08 (0.68-1.71) | |||

Q4 | 79 | 1.73 | 1.62 (1.05-2.50) | |||

Per 0.1 | 1.42 | 1.36 (1.11-1.66) | ||||

P_{trend} = 0.003 | ||||||

P_{heterogeneity} = 0.43 |

NOTE: Both adjusted and unadjusted RRs were stratified by 5-year age at entry groups, sex, and country.

*P*_{heterogeneity}is a test for heterogeneity in RR between countries.↵* Adjusted for smoking and diabetes and by sex-specific height quartile (weight, waist, hip and waist: hip ratio only).

↵† Quartiles: males, <170, 170 to <175, 175 to <180, and ≥180 cm; females, <158, 158 to <162, 162 to <167, and ≥167 cm.

↵‡ Quartiles: males, <73, 73 to <80, 80 to <88, and ≥88 kg; females, <58, 58 to <64, 64 to <72, and ≥72 kg.

↵§ Quartiles: males, <97, 97 to <100, 100 to <105, and ≥105 cm; females, <95, 95 to <101, 101 to <107, and ≥107 cm.

↵∥ Quartiles: males, <88, 88 to <94, 94 to <101, and ≥101 cm; females, <73, 73 to <79, 79 to <88, and ≥88 cm.

↵¶ Quartiles: males, <0.90, 0.90 to <0.94, 0.94 to <0.98, and ≥0.98; females, <0.75, 0.75 to <0.79, 0.79 to <0.84, and ≥0.84.