Table 1.

Adjusted ORs and 95% CIs for breast cancer associated with 15-F2t-IsoP and 8-oxodG levels in urine

Risk factorCases (%)Controls (%)Age-adjusted OR* (95% CI)Multivariable-adjusted OR (95% CI)
15-F2t-IsoP (nmol/mmol creatinine)
    <0.4568 (17)100 (25)1.001.00
    0.45-0.6488 (22)100 (25)1.26 (0.82-1.92)1.25 (0.81-1.94)
    0.64-0.99118 (30)100 (25)1.59 (1.05-2.41)1.53 (0.99-2.35)
    ≥0.99126 (31)101 (25)1.69 (1.12-2.55)1.88 (1.23-2.88)
P = 0.007P = 0.002
8-OxodG (nmol/mmol creatinine)
    <18.85107 (27)99 (25)1.001.00
    18.85-27.92111 (28)100 (25)1.01 (0.69-1.49)0.99 (0.64-1.51)
    27.92-38.2892 (23)100 (25)0.80 (0.54-1.19)0.75 (0.48-1.16)
    ≥38.2890 (22)100 (25)0.79 (0.53-1.18)0.79 (0.51-1.22)
P = 0.15P = 0.16
  • * Adjusted for reference age.

  • For 15-F2t-IsoP, the model was adjusted for age, average physical activity level and BMI; for 8-oxodG, the model was adjusted for age, average physical activity level, fruit and vegetable intake, average lifetime alcohol intake, active smoking status, menopausal status, and BMI.