Table 1.

Hereditary syndromes and genes associated with pancreatic cancer

SyndromeGene(s)Chromosome locationRefs.
Hereditary breast cancer, early onset 2BRCA213q12(19, 21-23, 42)
Familial atypical multiple mole melanoma syndromeCDKN2A/p169p21(43, 44)
Peutz-Jeghers syndromeSTK11/LKB119p13(45)
Fanconi anemia syndromeFANCC9q22(24, 46, 47)
FANCG9p13
Hereditary pancreatitisPRSS17q35(48, 49)
Hereditary nonpolyposis colorectal cancerhMSH22p15(50)
hMLH13p25
hPMS27p1
hMSH62p16
Cystic fibrosis (heterozygotes)CFTR7q31(51)