Table 4.

ORs and 95% CIs of colorectal cancer for plasma C-reactive protein

Quartiles of plasma C-reactive protein
Lowest (<0.24 mg/L)Second (0.24-0.45 mg/L)Third (0.46-0.95 mg/L)Highest (≥0.96 mg/L)Ptrend
Colorectal cancer
    Cases/controls64/17197/17988/178106/169
    OR (95% CI)1.0 (reference)1.5 (0.99-2.2)1.3 (0.85-2.0)1.6 (1.1-2.5)0.053
Colon cancer
    Cases/controls46/11059/12959/12080/120
    OR (95% CI)1.0 (reference)1.1 (0.71-1.9)1.2 (0.73-2.0)1.6 (0.99-2.7)0.041
Proximal colon cancer
    Cases/controls26/5429/6426/5737/54
    OR (95% CI)1.0 (reference)1.1 (0.57-2.2)1.0 (0.49-2.1)1.6 (0.79-3.3)0.18
Distal colon cancer
    Cases/controls17/5428/6031/5942/63
    OR (95% CI)1.0 (reference)1.2 (0.53-2.6)1.4 (0.63-3.3)1.6 (0.77-3.5)0.16
Rectal cancer
    Cases/controls18/6138/5029/5826/49
    OR (95% CI)1.0 (reference)2.4 (1.2-4.9)1.4 (0.63-3.2)1.4 (0.63-3.3)0.82
  • NOTE: ORs were estimated using matched pairs with adjustment for pack years of smoking (continuous), BMI (continuous), alcohol consumption (g/wk ethanol; continuous), physical exercise (less than once a week, or once a week or more), and family history of colorectal cancer.