Table 5.

OR for HCC and corresponding 95% CI by alcohol drinking, tobacco smoking and serologic markers of HBV and HCV (229 cases and 431 controls); Italy, 1999-2002

HBsAg and anti-HCVHBsAg+ and/or anti-HCV+
Maximal lifetime alcohol intake (drinks/wk)
    <14
        Ca/Co11:16451:24
        OR (95% CI)1*28.82 (12.84-64.69)
    14-34
        Ca/Co9:14182:19
        OR (95% CI)0.68 (0.26-1.76)47.60 (20.76-109)
    ≥35
        Ca/Co37:7839:5
        OR (95% CI)4.96 (2.19-11.24)74.36 (22.89-242)
Tobacco smoking
    Never/former
        Ca/Co42:281113:37
        OR (95% CI)1*23.42 (13.50-40.63)
    Current
        Ca/Co15:10259:11
        OR (95% CI)1.02 (0.53-1.97)44.27 (19.73-99.34)
  • NOTE: OR and 95% CI were adjusted for gender, age, center, and education.

  • Abbreviations: Ca, cases; Co, controls.

  • * Reference category.