Table 2.

OR (95% CI) of breast cancer according to quartiles of energy-adjusted folate, vitamin B6, and vitamin B12 intake

Quartiles of intake
1234P trend
Folate
Cases/controls162/347113/34897/349103/347
Median intake (μg/d)224303362454
    Age-adjusted1.000.65 (0.49-0.87)0.56 (0.42-0.76)0.62 (0.46-0.83)0.0007
    Multivariable-adjusted*1.000.77 (0.56-1.05)0.68 (0.48-0.94)0.64 (0.45-0.90)0.009
Vitamin B6
Cases/controls161/348100/350103/337111/356
Median intake (mg/d)1.061.261.401.60
    Age-adjusted1.000.56 (0.42-0.75)0.61 (0.45-0.82)0.69 (0.52-0.91)0.01
    Multivariable-adjusted*1.000.67 (0.49-0.92)0.76 (0.55-1.05)0.84 (0.61-1.13)0.41
Vitamin B12
Cases/controls159/352139/343107/34870/348
Median intake (μg/d)2.614.035.687.46
    Age-adjusted1.000.83 (0.63-1.10)0.62 (0.46-0.83)0.40 (0.29-0.55)<0.0001
    Multivariable-adjusted*1.000.80 (0.59-1.10)0.51 (0.36-0.73)0.32 (0.22-0.49)<0.0001
  • * Adjusted for age, socioeconomic status, family history of breast cancer, menopausal status, parity, availability of BMI, total caloric intake, dietary fiber carbohydrate intake, and polyunsaturated fat intake.