Table 1.

Odds ratios (95% confidence intervals) of colorectal, colon, and rectal cancer by quartiles of serum adiponectin

Odds ratios (95% confidence intervals)
Quartile 1Quartile 2Quartile 3Quartile 4Ptrend*
Colorectal cancer
    Adiponectin (μg/mL)≤4.64.6-6.36.3-8.9>8.9
    Cases/controls99/9577/96120/9585/950.97
    Crude model1.000.8 (0.5-1.2)1.2 (0.8-1.7)0.9 (0.6-1.3)
    Adjusted model1.0008 (0.5-1.2)1.2 (0.8-1.8)0.9 (0.6-1.4)
Colon cancer
    Adiponectin (μg/mL)≤4.64.6-6.36.3-8.9>8.9
    Cases/controls53/5944/5983/6057/590.30
    Crude model1.000.8 (0.5-1.4)1.5 (0.9-2.4)1.1 (0.7-1.8)
    Adjusted model1.000.8 (0.5-1.4)1.6 (1.0-2.6)1.2 (0.7-1.9)
Rectal cancer
    Adiponectin (μg/mL)≤4.74.7-6.46.4-8.7>8.7
    Cases/controls44/3635/3634/3631/360.30
    Crude model1.000.8 (0.4-1.5)0.8 (0.4-1.5)0.7 (0.3-1.4)
    Adjusted model1.000.7 (0.4-1.4)0.7 (0.4-1.4)0.6 (0.3-1.3)
  • NOTE: Conditional logistic regression, with quartile 1 as referent, cutoff points of adiponectin concentrations based on adipokine distribution in the controls.

  • * Test for linear trend in odds ratios over quartiles by assigning quantitative scores (1, 2, 3, and 4).

  • Adjusted for levels of leptin and C-peptide (after ln-transformation).