Table 1.

Expression of matriptase and HAI-1 in normal human prostate, BPH, PIN, and adenocarcinoma specimens

Specimen typeMatriptase staining intensity
HAI-1 staining intensity
TotalNoneWeakModerateStrongPTotalNoneWeakModerateStrongP
Total481162011401314121
Normal651000.05*611400.05*
BPH63030162770
PIN403100.05*53200
Carcinoma (all grades)323216110.0015*1374110.05*
Grade 12002021100
Grade 210205384211
Grade 22012980.01*32100
  • NOTE: The expression of matriptase and HAI-1 was evaluated as staining of the tissue as none (0), weak (1), moderate (2), and strong (3). Fisher exact test was used to examine the association between staining intensity and tissue type or staining intensity and tumor grade (for tumor specimen only).

  • * P < 0.05 was considered significant.