Table 4.

RR and 95% CI of prostate cancer in relation to dairy food and lactose intake in the Health Professionals Follow-up Study (1986-2002)

Dairy food intake, quintiles (median servings/d)
Ptrend
0.501.051.572.283.72
Total prostate cancer
    Cases648713696771716
    Multivariable model
        RR (95% CI)1.001.04 (0.93-1.15)1.02 (0.91-1.14)1.11 (0.99-1.24)1.07 (0.95-1.20)0.20
    Multivariable model + calcium
        RR (95% CI)1.001.03 (0.92-1.15)1.00 (0.89-1.13)1.09 (0.96-1.23)1.05 (0.91-1.21)0.44
Advanced prostate cancer
    Cases8111690111125
    Multivariable model
        RR (95% CI)1.001.25 (0.94-1.67)0.95 (0.70-1.29)1.08 (0.80-1.46)1.21 (0.89-1.64)0.39
    Multivariable model + calcium
        RR (95% CI)1.001.25 (0.93-1.69)0.93 (0.67-1.29)1.04 (0.74-1.45)1.08 (0.75-1.55)0.99
Lactose intake, quintiles (median g/d)
Ptrend

3.8
7.7
12.0
17.5
31.1

Total prostate cancer
    Cases608656720766794
    Multivariable model
        RR (95% CI)1.001.02 (0.91-1.14)1.07 (0.96-1.19)1.11 (0.99-1.23)1.13 (1.02-1.26)0.01
    Multivariable model + calcium
        RR (95% CI)1.001.02 (0.91-1.15)1.07 (0.95-1.21)1.12 (0.98-1.27)1.18 (1.02-1.35)0.02
Advanced prostate cancer
    Cases8210394109135
    Multivariable model
        RR (95% CI)1.001.14 (0.85-1.52)0.99 (0.73-1.34)1.08 (0.80-1.44)1.35 (1.02-1.79)0.03
    Multivariable model + calcium
        RR (95% CI)1.001.15 (0.84-1.56)1.01 (0.72-1.40)1.10 (0.78-1.55)1.36 (0.95-1.97)0.09
  • NOTE: Multivariable RR controlled for age, time period, body mass index at age 21, vigorous physical activity, height, cigarette pack-years in the previous 10 years, family history of prostate cancer, history of diabetes mellitus, race, and intake of total calories, red meat, fish, α-linolenic acid, zinc supplements, and tomato sauce.

    Dairy foods based on servings/day of skim/low fat milk, whole milk, cream, sour cream, sherbet ice milk, ice cream, yogurt, cottage cheese, cream cheese, other cheese.