Table 4.

Risk of kidney cancer associated with recreational physical activity, BMI, and energy intake, by age group (years), NECSS, Canada, 1994-1997

Histologic subtypeVariableAge, <50
Age, 50 to <65
Age, ≥65
CasesControlsOR (95% CI)*CasesControlsOR (95% CI)*CasesControlsOR (95% CI)*
Renal cellBMI (kg/m2)
    18.5 to <25514431.00744661.00704901.00
    <18.54232.06 (0.65-6.55)5132.33 (0.79-6.87)1270.26 (0.03-1.95)
    25 to <30622701.80 (1.16-2.81)1343942.14 (1.54-2.96)1185141.62 (1.16-2.26)
    ≥30261001.90 (1.09-3.29)801872.80 (1.92-4.07)511632.30 (1.51-3.51)
    Ptrend0.004<0.0001<0.0001
Total calorie intake (kcals/wk)
    <10,166342081.00722721.00472941.00
    10,166 to <12,762401921.27 (0.74-2.16)682650.92 (0.62-1.36)593181.15 (0.75-1.76)
    12,762 to <15,895322100.99 (0.57-1.71)742770.96 (0.65-1.42)542881.16 (0.74-1.80)
    ≥15,895382271.09 (0.64-1.87)812501.05 (0.71-1.55)802981.70 (1.13-2.56)
    Ptrend0.990.750.011
Physical activity (MET-hour/wk)
    <6.3341851.00722621.00633311.00
    6.3 to <17.0382161.01 (0.59-1.72)712710.94 (0.63-1.38)612891.09 (0.73-1.64)
    17.0 to <34.4321940.84 (0.48-1.48)772960.99 (0.67-1.45)582861.04 (0.69-1.56)
    ≥34.4402440.92 (0.53-1.59)752371.08 (0.73-1.61)592951.04 (0.68-1.59)
    Ptrend0.640.630.91
Non–renal cellBMI (kg/m2)
    18.5 to <25114431.00154661.00134901.00
    25 to <30132701.84 (0.78-4.32)243941.97 (1.00-3.87)205141.70 (0.80-3.58)
    ≥3071002.97 (1.08-8.15)111871.85 (0.81-4.22)141633.86 (1.69-8.80)
    Ptrend0.0280.0880.002
Total calorie intake (kcals/wk)
    <10,16652081.00142721.00112941.00
    10,166 to <12,76271921.83 (0.55-6.09)112650.80 (0.34-1.85)93180.75 (0.30-1.88)
    12,762 to <15,89592102.08 (0.66-6.58)132770.90 (0.40-2.03)112881.03 (0.41-2.56)
    ≥15,895102272.19 (0.70-6.88)132501.03 (0.45-2.33)172981.72 (0.76-3.86)
    Ptrend0.180.890.12
Physical activity (MET-hour/wk)
    <6.351851.0092621.00183311.00
    6.3 to <17.0132161.98 (0.67-5.85)172711.80 (0.76-4.25)112890.62 (0.27-1.39)
    17.0 to <34.471941.26 (0.38-4.23)112961.07 (0.42-2.70)102860.65 (0.28-1.47)
    ≥34.462440.78 (0.22-2.74)142371.43 (0.58-3.53)92950.60 (0.25-1.41)
    Ptrend0.380.790.23
  • * OR adjusted for age, province, gender, education, smoking pack-years, vegetable intake, and self-reported exposure to pesticides, herbicides, vinyl chloride, benzidine, benzene, mineral or cutting oil, and dyestuffs. Physical activities, BMI, and total calorie intake are adjusted for each other.