Table 5.

Physical activity and risk of colon cancer by BMI and energy intake, total study population

Type of activityBMI <25
BMI ≥25-<30
BMI ≥30
No. casesNo. person-yearsAge- and center-stratified hazard ratios (95% CI)*Multivariate hazard ratios (95% CI)No. casesNo. person-yearsAge- and center-stratified hazard ratios (95% CI)*Multivariate hazard ratios (95% CI)No. casesNo. person-yearsAge- and center-stratified hazard ratios (95% CI)*Multivariate hazard ratios (95% CI)
Inactive73246,5111.01.063148,5171.01.02648,1271.01.0
Moderately inactive179554,1500.84 (0.63-1.11)0.86 (0.64-1.15)159285,3350.97 (0.71-1.31)0.95 (0.69-1.29)59102,9780.78 (0.51-1.33)0.82 (0.50-1.33)
Moderately active179427,1240.85 (0.63-1.13)0.88 (0.66-1.19)177359,9550.79 (0.58-1.07)0.78 (0.57-1.07)80158,5460.78 (0.51-1.29)0.83 (0.51-1.34)
Active24111,5970.60 (0.38-0.96)0.63 (0.39-1.01)3793,5890.81 (0.54-1.23)0.81 (0.53-1.24)1934,2411.01 (0.55-1.84)1.03 (0.56-1.90)
Ptrend0.080.140.070.080.850.98
<1,827 kcal/d≥1,827-<2,351 kcal/d>2,351 kcal/d
Inactive46148,4841.01.065150,7381.01.051143,9331.01.0
Moderately inactive130311,9130.89 (0.63-1.27)0.95 (0.66-1.36)151327,2040.86 (0.63-1.17)0.85 (0.62-1.16)116303,3460.91 (0.65-1.27)0.93 (0.66-1.31)
Moderately active136318,8770.75 (0.52-1.07)0.81 (0.56-1.18)136312,0590.66 (0.48-0.91)0.66 (0.48-0.92)164314,6891.09 (0.79-1.51)1.13 (0.81-1.57)
Active1961,9790.74 (0.42-1.27)0.81 (0.47-1.41)2272,6100.58 (0.36-0.96)0.59 (0.36-0.97)39104,8370.96 (0.63-1.46)1.01 (0.66-1.55)
Ptrend0.070.190.0020.0030.610.44
  • * Base models are stratified by age and center and mutually adjusted for each type of physical activity (occupational, recreational, and household).

  • Multivariate models are stratified by age and center and adjusted for energy (kilocalories per day in quartiles), education (none, primary school, technical/professional school), smoking (never, former, current, unknown), and fiber (grams per day in quartiles).