Table 3.

Physical activity and risk of colon and rectal cancers, by type of activity for total study population

Type of activityColon cancer, total study population
Rectal cancer, total study population
No. casesNo. person-yearsAge- and center-stratified hazard ratio (95% CI)*Multivariate hazard ratio (95% CI)Quartile definitions/cut pointsNo. casesNo. person-yearsAge- and center-stratified hazard ratio (95% CI)*Multivariate hazard ratio (95% CI)
Total physical activity
Inactive162443,1551.01.0Inactive91442,8641.01.0
Moderately inactive397942,4630.91 (0.75-1.10)0.92 (0.76-1.12)Moderately inactive192941,6841.01 (0.78-1.31)1.02 (0.78-1.32)
Moderately active436943,6260.84 (0.69-1.01)0.86 (0.70-1.04)Moderately active246944,9561.00 (0.78-1.29)1.02 (0.79-1.32)
Active80239,4270.76 (0.58-1.00)0.78 (0.59-1.03)Active58239,3181.01 (0.72-1.40)1.02 (0.73-1.44)
Ptrend0.020.04Ptrend0.980.91
Occupational activity
Sedentary249727,7851.01.0Sedentary142727,3631.01.0
Standing202689,0870.96 (0.80-1.17)0.98 (0.81-1.19)Standing109688,7121.11 (0.86-1.43)1.11 (0.85-1.43)
Manual/heavy manual110274,1660.89 (0.71-1.12)0.91 (0.72-1.15)Manual/heavy manual71274,0150.97 (0.72-1.29)0.96 (0.71-1.30)
Nonworker514879,6340.90 (0.75-1.08)0.91 (0.75-1.09)Nonworker265878,7341.15 (0.90-1.47)1.16 (0.90-1.49)
Ptrend§0.290.38Ptrend§0.970.82
Household activity (MET-h/wk)
<19.5289673,3161.01.0<19.5150672,7661.01.0
≥19.5-<39.6281682,0230.94 (0.80-1.12)0.95 (0.80-1.12)≥19.5-<39.6157681,5761.02 (0.81-1.28)1.02 (0.81-1.28)
≥39.6-<73.9272659,3170.90 (0.76-1.07)0.90 (0.76-1.07)≥39.6-<73.9167658,9121.09 (0.87-1.38)1.10 (0.87-1.39)
≥73.9252618,2260.92 (0.76-1.13)0.93 (0.76-1.13)≥73.9125617,7470.97 (0.74-1.26)0.98 (0.75-1.29)
Ptrend0.340.35Ptrend0.970.88
Recreational activity (MET-h/wk)
<12.0317675,2161.01.0<12.8139488,1571.01.0
≥12.0-<24.8255665,7160.83 (0.70-0.98)0.85 (0.71-1.00)≥12.8-<24.0144490,9031.14 (0.90-1.44)1.15 (0.90-1.46)
≥24.8-<42.8258658,5470.81 (0.68-0.96)0.83 (0.70-0.98)≥24.0-<42.0158477,4891.20 (0.94-1.51)1.22 (0.96-1.54)
≥42.8264633,4030.85 (0.71-1.01)0.88 (0.74-1.05)≥45.8158426,4191.18 (0.92-1.50)1.21 (0.94-1.54)
Ptrend0.050.13Ptrend0.180.12
  • * Base models are stratified by age and center and mutually adjusted for each type of physical activity (occupational, recreational, and household).

  • Multivariate models are stratified by age and center and adjusted for energy (kilocalories per day in quartiles), education (none, primary school, technical/professional school), smoking (never, former, current, unknown), height (centimeters in tertiles), weight (kilograms in tertiles), and fiber (grams per day in quartiles).

  • Multivariate models are stratified by age and center and adjusted for energy (kilocalories per day in quartiles), education (none, primary school, technical/professional school), smoking (never, former, current, unknown), height (centimeters in tertiles), weight (kilograms in tertiles), fiber (grams per day in quartiles), and fish intake (grams per day in quartiles).

  • § Test for trend in occupational activity excluded all study participants categorized as nonworkers, missing, or unknown.