Table 1.

Minor allele frequencies of NAT2 polymorphisms in Romanians, Kyrgyz, Caucasians, and Chinese

Sequence variantMinor allele frequency, % (95% confidence interval)
P, χ2 test
Romanians, n = 140Caucasians,*n = 31Kyrgyz, n = 290Chinese,n = 24Romanians vs CaucasiansKyrgyz vs ChineseRomanians vs Kyrgyz
282T37.1 (25.2-50.3)30.0 (24.7-35.7)37.6 (33.6-41.7)N.d.0.52N.d.0.10
590A (197Q)33.9 (22.3-47.0)28.6 (23.4-34.3)26.6 (23.0-30.4)33.3 (20.4-48.4)0.490.490.62
341C (114T)43.5 (31.0-56.7)37.8 (32.2-43.8)19.3 (16.2-22.8)6.3 (1.3-17.2)0.10<0.0001<0.0001
481T43.3 (30.6-56.8)38.2 (32.5-44.2)19.1 (16.5-23.1)6.5 (1.4-17.9)0.490.08<0.0001
803G (268K)40.3 (28.1-53.6)36.8 (31.1-42.7)19.8 (16.7-23.3)N.d.0.86N.d.<0.0001
857A (286E)3.2 (0.4-11.2)1.4 (0.4-3.6)12.1 (9.5-15.0)6.3 (1.3-17.2)0.070.48<0.0001
3′ Untranslated region C10.0 (3.8-20.5)2.5 (1.0-5.1)1.3 (0.6-2.7)0 (0-0.7)0.040.420.32