Table 5.

Risk of colorectal cancer associated with the total number of risk alleles for ERCC6 R1213G and XPC R492H

No. risk alleles*No. casesNo. PYRR (95% CI)P
011116,1551.0
17710,0141.21 (0.88-1.68)0.24
2342,1232.57 (1.64-4.03)0.00004
3+51508.48 (2.67-26.98)0.0003
Ptrend0.00003
  • * Risk alleles are ERCC6 1213G and XPC 492H.

  • Adjusted for age (continuous) and race.