Table 1.

Demographic, treatment, and genotype characteristics in different histologic cell types of lung cancer patients

CharacteristicHistologic cell types
All patients (N = 373), n (%)Adenocarcinoma (N = 180), n (%)Squamous (N = 108), n (%)Others (N = 85), n (%)P
Age (y)*69 (31-89)69 (35-86)70 (47-89)69 (31-88)0.32
Gender, female182 (49)97 (54)40 (37)45 (53)0.01
Smoking status
    Never26 (7)17 (9)1 (1)8 (9)<0.001
    Ex-smokers202 (54)89 (49)54 (50)59 (69)
    Current smokers145 (39)74 (41)53 (49)18 (21)
Clinical stage
    IA194 (52)104 (58)40 (37)50 (59)<0.01
    IB109 (29)43 (24)41 (38)25 (29)
    IIA14 (4)10 (5)31 (1)
    IIB56 (15)23 (13)24 (22)9 (11)
Surgery type
    Wedge90 (24)50 (28)23 (21)17 (20)<0.001
    Lobectomy232 (62)117 (65)57 (53)58 (68)
    Others51 (14)13 (7)28 (26)10 (12)
Radiation/chemotherapy30 (8)12 (7)11 (10)7 (8)0.57
Surgery season
    Winter107 (29)53 (29)32 (30)22 (26)0.98
    Spring/fall143 (38)68 (38)41 (38)34 (40)
    Summer123 (33)59 (33)35 (32)29 (34)
VDR Cdx-2 G>A polymorphism
    G/G201 (54)87 (48)66 (61)48 (57)0.20
    G/A144 (39)78 (44)37 (34)29 (34)
    A/A28 (7)15 (8)5 (5)8 (9)
VDR FokI C>T polymorphism
    C/C141 (38)68 (38)44 (41)29 (34)0.63
    C/T170 (45)78 (43)48 (44)44 (52)
    T/T62 (17)34 (19)16 (15)12 (14)
VDR BsmI C>T polymorphism
    C/C119 (32)54 (30)33 (31)32 (38)0.54
    C/T182 (49)92 (51)50 (46)40 (47)
    T/T72 (19)34 (19)25 (23)13 (15)
  • NOTE: Among the population, 340 patients were Caucasians, 12 patients were non-Caucasians, and 21 patients were missing the race information. Except for age, all of the other values are tested by χ2 test or Fisher's exact test.

  • * Median (range), tested by Kruskal-Wallis test.

  • Seasons include winter (the low sun exposure months of November-February), spring/fall (the intermediate sun exposure months of March, April, September, and October), and summer (the high sun exposure months of May-August).