Table 4.

Associations between BMI and low-grade and high-grade prostate cancer, stratified by age and family history of prostate cancer, the PCPT

VariablesGraden (cases/controls)BMI (kg/m2), OR (95% CI)
Ptrend
<25.025.0-26.927.0-29.9≥30
Age*
    <65Low388/2,7981.000.99 (0.80-1.23)0.94 (0.77-1.16)0.89 (0.72-1.11)0.27
High112/2,7981.000.88 (0.61-1.26)0.92 (0.66-1.28)1.03 (0.73-1.45)0.82
    ≥65Low912/5,5241.000.73 (0.56-0.94)0.80 (0.62-1.03)0.72 (0.55-0.96)0.03
High409/5,5241.001.03 (0.70-1.51)1.23 (0.86-1.78)1.56 (1.07-2.27)0.01
Family history
    NoLow1,020/7,0181.000.89 (0.74-1.07)0.86 (0.72-1.03)0.81 (0.67-0.98)0.03
High418/7,0181.000.95 (0.71-1.27)1.08 (0.82-1.42)1.29 (0.97-1.71)0.07
    YesLow280/1,3041.000.81 (0.56-1.18)0.97 (0.68-1.38)0.87 (0.60-1.26)0.67
High103/1,3041.001.06 (0.58-1.93)1.14 (0.64-2.04)1.35 (0.76-2.41)0.28
  • * Adjusted for race, diabetes, treatment, and family history of prostate cancer in first-degree relatives.

  • Adjusted for age, race, diabetes, and treatment.