Table 1.

OR and 95% CIs for lung cancer and histology-specific lung cancer by NQO1 genotype

NQO1 genotype
CT + TTCC
All
    Cases109244
    Controls117243
    Age-adjusted OR (95% CI)1.00 (reference)1.09 (0.80-1.50)
    Multivariate OR (95% CI)*1.00 (reference)1.07 (0.78-1.49)
Adenocarcinoma
    Cases1840
    Controls117243
    OR (95% CI)*1.001.10 (0.60-2.02)
Small-cell carcinoma
    Cases2039
    Controls117243
    OR (95% CI)*1.000.97 (0.53-1.75)
Squamous cell carcinoma
    Cases50107
    Controls117243
    OR (95% CI)*1.001.03 (0.68-1.55)
  • * Estimated by unconditional logistic regression and adjusted for age at randomization, number of cigarettes smoked per day, years smoked, and intervention assignment.