Table 2.

RRs of invasive epithelial ovarian cancer according to baseline and long-term coffee consumption in the Swedish Mammography Cohort

Coffee consumption (cups/d)P for trend*One cup of coffee per day
<112-3≥4
Baseline intake
    No. cases264717652301
    No. person-years of follow-up82,053121,086548,798168,470920,407
    Age-adjusted RR (95% CI)1.001.11 (0.68-1.81)0.99 (0.65-1.51)1.09 (0.67-1.77)0.971.01 (0.90-1.12)
    Multivariate RR (95% CI)1.001.08 (0.66-1.73)0.96 (0.62-1.47)1.02 (0.62-1.69)0.840.99 (0.88-1.11)
Long-term intake
    No. cases245117749301
    Age-adjusted RR (95% CI)1.001.16 (0.71-1.89)0.99 (0.65-1.53)1.12 (0.68-1.84)0.980.98 (0.88-1.08)
    Multivariate RR (95% CI)1.001.13 (0.69-1.86)0.97 (0.62-1.51)1.07 (0.64-1.79)0.850.98 (0.88-1.09)
  • * P for trend calculated by using the median value of each category of coffee consumption as a single continuous variable.

  • Multivariate RRs are adjusted for age in months (continuous), body mass index (quartiles), education (less than high school, high school, university), parity (nulliparous, 1-2 children, ≥3 children), oral contraceptive use (ever, never), and intakes of total energy (continuous), fruit (quartiles), vegetables (quartiles), milk (quartiles), and tea (<1 cup/mo, 1 cup/mo to <1 cup/d, 1 cup/d, and ≥2 cups/d).