Table 1.

Characteristics of study population

CharacteristicControls (n = 329)Cases (n = 234)P*
Age, mean (range)53.7 (35-79)55.3 (35-80)0.08
Foreign born, % (n)60.8 (200)45.3 (106)<0.001
Grandparents' place of birth, % (n)
    Mexico51.4 (169)45.3 (106)
    Central America18.8 (62)13.3 (31)0.37
    South America4.6 (15)6.4 (15)0.22
    Caribbean3.7 (12)2.7 (6)0.66
    United States5.2 (17)6.0 (14)0.47
    Mixed origin16.4 (54)26.5 (62)0.007
Education, % (n)
    Some high school or less51.4 (169)34.2 (80)
    High school graduation17.3 (57)20.9 (49)0.011
    Some college16.1 (53)29.9 (70)<0.001
    College graduation or higher15.2 (50)14.5 (35)0.13
No. full-term pregnancies, mean ± SD3.4 ± 2.42.7 ± 1.80.0012
Age at first full-term pregnancy, mean ± SD22.9 ± 5.523.7 ± 5.30.15
History of hormone therapy use, % (n)38.2 (124)45.0 (103)0.11
Age at menarche, mean ± SD12.7 ± 1.612.5 ± 1.80.06
Postmenopausal status, % (n)55.9 (184)57.7 (135)0.34
Age at natural menopause, mean ± SD47.4 ± 5.348.6 ± 5.00.11
  • * Ps for comparison of proportions were obtained using χ2 tests. Ps for comparison of continuous variables were obtained using t tests. Ps for comparison of ordinal variables (number of full-term pregnancies) were obtained using rank sum tests.

  • Women with grandparents from more than one of the five regions (Mexico, Central America, South America, Caribbean, United States).