Table 1.

p53 expression at baseline and at 3 months in forearm biopsies, AK lesions, and skin adjacent to previous SCC

GroupSamplenMean % p53 expression (SE)P*
Group 1: sun-damaged forearm, no sunscreenBaseline3312.95 (2.80)0.30
3 mo3310.37 (2.53)
Group 1: sun-damaged forearm, sunscreenBaseline4312.28 (1.95)0.79
3 mo4311.07 (1.56)
Group 2: AK forearmBaseline3219.54 (2.88)0.59
3 mo3221.48 (3.03)
Group 2: AK lesionBaseline3027.18 (3.94)0.47
3 mo3021.81 (3.62)
Group 3: skin adjacent to previous SCCBaseline3010.51 (2.30)0.12
3 mo308.5 (2.25)
Group 3: forearm previous SCC forearmBaseline3215.41 (2.66)0.99
3 mo3215.56 (2.92)
  • * Wilcoxon signed rank test comparing baseline expression to 3 months expression.