Table 4.

Association of glioma and meningioma with genotype combinations formed by three polymorphisms in p53; promoter region (rs2287499), exon 4, codon 72 (rs1042522), and intron 6 (rs1625895)

GenotypeGlioma
Meningioma
Controls (n)
nOR (95% CI)nOR (95% CI)
CC-CC-CC1031.0 (reference)781.0 (reference)177
CC-CG-CC171.36 (0.68-2.72)131.36 (0.64-2.88)21
CG-CC-CC50.64 (0.23-1.81)50.85 (0.30-2.40)14
CG-CG-CC150.66 (0.34-1.26)160.87 (0.45-1.66)39
CC-CG-CT271.00 (0.59-1.72)130.65 (0.33-1.28)46
  • NOTE: Only the five most common combinations in which a prevalence of at least 3% is shown, because calculations of smaller groups were not meaningful.