Table 2.

Association of glioma and meningioma with polymorphisms in p53: promoter region (rs2287499), exon 4, codon 72 (rs1042522), and intron 6 (rs1625895)

GenotypeGlioma
Meningioma
Controls (n)
nOR (95% CI)nOR (95% CI)
Promoter region
    CC1661.0 (reference)1181.0 (reference)287
    CG + GG330.74 (0.47-1.16)371.17 (0.75-1.83)77
Exon 4, codon 72
    CC1161.0 (reference)851.0 (reference)211
    CG + CG821.02 (0.71-1.44)651.10 (0.74-1.61)147
Intron 6
    CC1541.0 (reference)1241.0 (reference)275
    CT + TT380.92 (0.59-1.42)310.93 (0.58-1.49)74
  • NOTE: Numbers of genotypes vary for different polymorphisms as there were different failure rates for the different genotypes.