Table 4.

Maternal smoking and TGCT risk

Overall
Seminoma
Nonseminoma
Cases/controlsOR* (95% CI)Cases/controlsOR* (95% CI)Cases/controlsOR* (95% CI)
Mother smoked
    No227/2491.082/2491.0145/2491.0
    Yes287/3111.0 (0.8-1.3)124/3111.2 (0.9-1.7)163/3110.9 (0.7-1.2)
        While pregnant151/1651.0 (0.8-1.4)64/1651.1 (0.8-1.7)87/1650.9 (0.7-1.3)
        While breast-feeding34/321.2 (0.7-2.0)12/321.0 (0.5-2.1)22/321.3 (0.7-2.3)
Age started smoking (y)
    Never227/2491.082/2491.0145/2491.0
    <17106/1141.0 (0.8-1.4)49/1141.3 (0.9-2.1)57/1140.9 (0.6-1.3)
    17-1876/811.0 (0.7-1.5)32/811.2 (0.7-1.9)44/810.9 (0.6-1.4)
    >18104/1151.0 (0.7-1.4)42/1151.0 (0.7-1.6)62/1150.9 (0.6-1.4)
Cigarettes/d
    Never227/2491.082/2491.0145/2491.0
    <1070/970.8 (0.5-1.1)30/970.9 (0.5-1.5)40/970.7 (0.4-1.1)
    10-1783/771.2 (0.8-1.7)33/771.2 (0.8-2.0)50/771.1 (0.8-1.7)
    >17130/1331.1 (0.8-1.5)60/1331.4 (0.9-2.1)70/1330.9 (0.6-1.3)
Duration of smoking (y)
    Never227/2491.082/2491.0145/2491.0
    <2299/1011.1 (0.8-1.5)41/1011.3 (0.8-2.1)58/1011.0 (0.6-1.4)
    22-32102/1031.1 (0.8-1.5)42/1031.3 (0.8-2.0)60/1030.9 (0.6-1.4)
    >3284/1040.9 (0.6-1.3)39/1041.0 (0.6-1.6)45/1040.8 (0.6-1.3)
Duration of smoking after son's birth (y)
    Never227/2491.082/2491.0145/2491.0
    <1587/1030.9 (0.7-1.3)34/1031.1 (0.7-1.7)53/1030.9 (0.6-1.3)
    15-2495/891.1 (0.8-1.6)39/891.5 (0.9-2.4)56/890.9 (0.6-1.4)
    >24104/1171.0 (0.7-1.4)50/1171.1 (0.7-1.7)54/1170.9 (0.6-1.4)
  • NOTE: Data taken from mothers' questionnaire.

  • * Adjusted for son's age (continuous), race, cryptorchism, and family history of testicular cancer.