Table 1.

Loci associated with prostate cancer aggressiveness

StudyLocusP value/LOD
Witte et al. (35)5q31.3-q33.330.0002
7q32.20.0007
19q120.0004
Goddard et al. (13)4q0.0004
1q24-q250.0001
1q42.2-q430.003
Xq12-q130.0005
Slager et al. (39)4q0.0001
19q13<0.00001
Paiss et al. (38)7q31-q330.002
Slager et al. (40)6q23.30.0009 (LOD 2.4)
5p13.1-5q11.20.004
Schaid et al. (31)19q13.31-q13.330.0007
20p13-p12.40.0006
Chang et al. (32)*Xq27-28HLOD 2.5
22q13HLOD 2.1
Stanford et al. (33)*22q11.1HLOD 2.2
22q12.3-q13.1HLOD 1.9
Schaid et al. (31)*20pLOD 2.5
  • * Aggressive prostate cancer based on Gleason score, stage, PSA, and death from prostate cancer.