Table 3.

HLA markers independently associated with adult glioblastoma multiforme in multivariable analyses

HLA factors*Model 1
Model 2
OR (95% CI)POR (95% CI)P
B*07-Cw*072.79 (1.56-5.00)<0.0012.78 (1.55-4.98)<0.001
HLA-B*137.07 (1.49-33.57)0.0147.53 (1.56-36.31)0.012
HLA-Cw*010.35 (0.12-1.03)0.0570.33 (0.11-0.99)0.047
  • * Initially identified through univariate analyses (Table 2).

  • Model 1 includes all independent markers (i.e., those not explained by linkage disequilibrium); model 2 reflects further adjustment for age and gender.