Table 2.

HLA markers provisionally associated with adult glioblastoma multiforme (GBA) through univariate analyses

HLA marker*Distribution, {n (%)} in:
OR (95% CI)Univariate P
155 Cases157 Controls
HLA-B*0749 (31.6)24 (15.3)2.56 (1.48-4.44)<0.001
HLA-B*1310 (6.5)2 (1.3)5.34 (1.15-24.80)0.020
HLA-Cw*015 (3.2)14 (8.9)0.34 (0.12-0.97)0.044
B*07-Cw*0745 (29.0)21 (13.4)2.65 (1.49-4.71)<0.001
B*13-Cw*069 (5.8)2 (1.3)4.78 (1.02-22.48)0.035
  • * Alleles and haplotypes tentatively associated with GBM, based on nominal P ≤ 0.05. OR, odds ratio; CI, confidence interval. Note that neither Cw*07 alone nor Cw*06 alone is associated with GBM (see text).

  • Based on maximum likelihood Chi-Square test unless specified otherwise.

  • By 2-sided, Fisher's exact test.