Table 2.

Skin pigmentation characteristics and association of a nevus with cutaneous malignant melanoma (N = 932)

CharacteristicnN−* (%)nN+* (%)ORcrude (95% CI)ORadj (95% CI)
Nevus density (body diagrams)
    No nevi174 (75)57 (25)1.01.0
    Low299 (60)198 (40)2.0 (1.4-2.9)1.8 (1.3-2.6)
    Moderate92 (63)54 (37)1.8 (1.1-2.8)1.5 (0.9-2.4)
    High22 (47)25 (53)3.5 (1.8-6.6)3.1 (1.6-6.0)
    Ptrend0.00010.004
Nevi on back
    0-3209 (72)81 (28)1.01.0
    4-10151 (61)95 (39)1.6 (1.1-2.3)1.5 (1.1-2.2)
    11-25123 (61)79 (39)1.7 (1.1-2.4)1.4 (1.0-2.1)
    >25106 (56)83 (44)2.0 (1.4-3.0)1.7 (1.1-2.5)
    Ptrend0.00040.02
Facial freckles at age 10
    Few404 (62)247 (38)1.01.0
    Moderate160 (68)77 (33)0.8 (0.6-1.1)0.8 (0.6-1.1)
    Many26 (65)14 (35)0.9 (0.5-1.7)0.8 (0.4-1.6)
    Ptrend0.130.07
Skin propensity to burn
    Severe burn with blistering48 (68)23 (32)0.9 (0.5-1.5)1.0 (0.6-1.7)
    Severe burn, followed by peeling208 (61)133 (39)1.2 (0.9-1.6)1.2 (0.9-1.6)
    Mild burn, followed by tan272 (65)149 (35)1.01.0
    Tan, no burn45 (64)25 (36)1.0 (0.6-1.7)1.0 (0.6-1.8)
    Ptrend0.780.53
Skin tendency to tan
    Dark tan92 (60)62 (40)1.01.0
    Moderate tan225 (60)149 (40)1.0 (0.7-1.4)1.0 (0.7-1.5)
    Mild tan196 (70)85 (30)0.6 (0.4-1.0)0.7 (0.5-1.1)
    No suntan or freckling56 (64)32 (36)0.9 (0.5-1.5)1.0 (0.6-1.8)
    Ptrend0.060.25
  • * Counts may not sum to the total number of study subjects due to missing data.

  • Adjusted for study center, sex, and age.