Table 2.

Genotypes and allele frequencies for IGF1, IGFBP3, IRS1, IRS2, and VDR polymorphisms from population-based samples of Hispanic and non-Hispanic White women

Hispanic, n* (%)Non-Hispanic White, n* (%)P
IGF1 CA repeat
    19/19196 (43.4)708 (42.1)0.38
    19/other181 (40.0)770 (45.8)
    Other/other75 (16.6)205 (12.2)
    Other allele frequency0.370.35
IGFBP3 −202 C > A
    CC190 (41.3)494 (29.2)<0.001
    AC207 (45.0)833 (49.3)
    AA63 (13.7)362 (21.4)
    A allele frequency0.360.46
IRS1 G972R
    GG411 (89.5)1,481 (87.6)0.21
    GR47 (10.2)199 (11.8)
    RR1 (0.2)10 (0.6)
    R allele frequency0.050.06
IRS2 G1057D
    GG160 (34.7)689 (40.8)0.007
    GD222 (48.2)771 (45.7)
    DD79 (17.1)228 (13.5)
    D allele frequency0.410.36
VDR BsmI
    bb243 (53.3)593 (35.3)<0.001
    bB176 (38.6)811 (48.2)
    BB37 (8.1)277 (16.5)
    B allele frequency0.270.41
VDR FokI
    FF165 (36.4)617 (37.3)0.08
    Ff204 (45.0)824 (49.8)
    ff84 (18.5)214 (12.9)
    f allele frequency0.410.38
  • * Some genotype categories do not sum to the total due to missing data.

  • P values for differences in allele frequencies by ethnicity, from a test for difference in proportions.