Table 1.

Association of TGF-β1 gene polymorphisms with breast cancer risk, the Shanghai Breast Cancer Study

GenotypesCases, n (%)Controls, n (%)Unadjusted OR (95% CI)Adjusted OR* (95% CI)
C-509T
    CC260 (23.3)260 (21.6)1.01.0
    CT/TT858 (76.7)946 (78.4)0.91 (0.75-1.10)0.90 (0.74-1.10)
    CT559 (50.0)628 (52.0)0.89 (0.72-1.09)0.89 (0.72-1.10)
    TT299 (26.7)318 (26.4)0.94 (0.74-1.19)0.93 (0.73-1.17)
T + 29C
    TT258 (23.2)255 (21.5)1.01.0
    TC/CC856 (76.8)934 (78.5)0.91 (0.74-1.10)0.90 (0.73-1.10)
    TC554 (49.7)615 (51.7)0.89 (0.72-1.10)0.88 (0.71-1.09)
    CC302 (27.1)319 (26.8)0.94 (0.74-1.18)0.92 (0.72-1.17)
  • * Adjusted for age, education, age at menarche, menopausal status, age at menopause, age at first live birth, waist-to-hip ratio, and physical activity during the preceding 10 years.