Table 2.

Associations between prediagnostic plasma VEGF levels and risk of total prostate cancer

Tertile of prediagnostic VEGF level
Ptrend
123
VEGF levels (pg/mL) in controls, median (range)16.4 (2.5-31.3)48.9 (31.8-71.9)124.6 (72.3-5765.8)
Unmatched analysis*
    No. cases/controls155/173175/174174/1730.65
    OR (95% CI)1.00 (reference)1.10 (0.81-1.49)1.09 (0.80-1.49)
Matched analysis
    No. cases/controls145/161172/174167/1680.61
    OR (95% CI)1.00 (reference)1.10 (0.79-1.54)1.11 (0.79-1.56)
  • * Unconditional logistic regression, further adjusted for age, smoking, and duration of follow-up; 504 cases and 520 controls.

  • Conditional logistic regression; 484 cases and 503 controls, matched by age (±1 y; ±5 y for men ages >55 y) and smoking status (never, former, and current) at baseline.