Table 8.

Determinants of ER status of second breast cancer (BRCA1 and BRCA2 combined)

VariableOR (95% CI)P
Age of diagnosis0.97 (0.93-1.01)0.18
Tamoxifen use for first cancer (yes versus no)0.71 (0.24-2.05)0.52
Oophorectomy prior to second cancer (yes versus no)0.65 (0.21-2.04)0.46
ER status of first cancer (positive versus negative)8.70 (3.52-21.5)<0.0001
Gene (BRCA2 versus BRCA1)6.02 (2.29-15.9)0.0003