Table 5.

Association between grade of the first and second cancers

First grade 1First grade 2First grade 3Total
BRCA1
    Second grade 182515
    Second grade 2221721
    Second grade 32157592
    Total121997128
BRCA2
    Second grade 13407
    Second grade 20141327
    Second grade 317715
    Total4252049
  • NOTE: P value < 0.0001 (χ2 test) for BRCA1. P value = 0.003 (χ2 test) for BRCA2.