Table 1.

Cigarette consumption and nicotine, carbon monoxide exposure while smoking usual brand and light cigarettes

Week 1 (usual brand)Week 2 (light)Week 3 (Usual brand)Overall (P)Post hoc P
Week 1 versus week 2Week 1 versus week 3
CPD
    Mean22.527.522.90.010.020.97
    SD12.517.815.1
    95% CI(15.8-29.1)(18.0-37.0)(14.8-30.9)
Plasma* nicotine (ng/mL)
    Mean15.013.415.70.35
    SD7.15.67.6
    95% CI(11.3-18.8)(10.4-16.4)(11.5-19.9)
Plasma* cotinine (ng/mL)
    Mean2212012470.030.40.3
    SD90107117
    95% CI(174-269)(144-258)(183-312)
Blood COHb* (%)
    Mean4.54.34.80.12
    SD1.72.01.4
    95% CI(3.6-5.4)(3.2-5.4)(4.1-5.6)
Nicotine boost (ng/mL)
    Mean13.810.514.50.11
    SD7.27.611.4
    95% CI(10.0-17.7)(6.4-14.6)(8.2-20.9)
COHb boost (%)
    Mean0.690.630.780.08
    SD0.250.20.3
    95% CI(0.55-0.82)(0.53-0.73)(0.61-0.96)
  • Abbreviation: 95% CI, 95% confidence interval.

  • * Measurements before smoking the test cigarette.

  • Differences in concentrations before and after smoking the test cigarette.