Table 5.

Distribution of quantitative mammographic features by Wolfe categories, Guernsey IV study, United Kingdom

Quantitative mammographic feature
Wolfe grade
Median (interquartile range)N1P1P2DYPtrend*
Percent breast density15.2 (17.2)27.8 (14.2)43.3 (17.9)56.2 (16.2)<0.001
Total area of dense tissue (cm2)17.2 (17.0)29.7 (19.7)40.0 (26.3)43.9 (24.9)<0.001
Total area of lucent tissue (cm2)100.0 (68.6)78.8 (48.6)52.9 (37.8)35.5 (24.5)<0.001
Total area of the breast (cm2)120.9 (67.3)109.9 (55.6)96.3 (56.3)79.3 (40.9)<0.001
Total volume of the breast (cm3)850 0 (577.2)755.8 (466.1)646.5 (454.4)486.3 (320.9)<0.001
Fractal dimension2.96 (0.10)2.91 (0.08)2.86 (0.09)2.87 (0.08)<0.001
Regional skewness0.41 (0.42)0.48 (0.49)0.52 (0.53)0.58 (0.59)<0.001
Lacunarity5.03 (0.22)5.00 (0.20)4.98 (0.25)4.88 (0.21)<0.001
  • * Nonparametric test for linear trend across ordered categories.