Table 2.

Levels of serum markers

Analytes/patientsHealthy controlsOvarian cancerBenign
EGFmean ± SE223.8 ± 11.46110.7 ± 15.58***98.6 ± 12.35***
median (range)238 (29.8-402.6)74.9 (0-396.9)94.9 (0-276.4)
IL-6mean ± SE8.8 ± 2.5064.2 ± 12.72***28.0 ± 9.3***
median (range)0 (0-64.1)23.8 (0-280.2)7.6 (0-275.3)
G-CSFmean ± SE21.8 ± 8.4449.2 ± 12.04NS77.4 ± 14.04**
median (range)0 (0-257.6)0 (0-290.8)0 (0-339.1)
IL-8mean ± SE10.2 ± 1.6824.0 ± 5.98**12.4 ± 3.11
median (range)6 (2.3-51.4)9.6 (2.0-180.6)7.6 (3.0-127.8)
VEGFmean ± SE90.7 ± 10.52153.5 ± 19.95*258.8 ± 26.04*
median (range)67 (18-306)106 (28-552)218 (48-662)
CA-125mean ± SE10.4 ± 2.28153.7 ± 44.04***51.8 ± 13.23**
median (range)6.0 (0-87)51.0 (0-1412)16.0 (0-372)
MCP-1mean ± SE341.8 ± 21.34210.3 ± 20.54***196.3 ± 16.06***
median (range)326.8 (135.5-695.7)172.9 (17.1-502.3)178.2 (44.9-434.6)
  • NOTE: Comparison of ovarian cancer or benign patients with controls: *, P < 0.05; **, P < 0.01; ***, P < 0.001; NS, not significant.