First authorReferenceCountryHPV DNA sourcePCR primersCases nLSIL/CIN1HPV prevalence (% of all LSILs tested)
Any16315153565266586183933593545
Africa
    de Vuyst HSex Transm Dis (2002)KenyaCellsSPF10300/3060.013.33.33.310.03.313.33.36.70.06.70.00.00.023.33.3
    La Ruche GInt J Cancer (1998)Ivory CoastCellsMY09/11151151/068.210.65.30.02.62.63.33.36.02.05.31.31.32.0
    Thomas JOBr J Cancer (2003)NigeriaCellsGP5+/6+3434/038.25.92.92.92.92.90.05.92.92.90.00.00.00.00.0
    Xi LFInt J Cancer (2003)SenegalCellsMY09/118686/051.28.11.21.23.51.23.51.29.32.34.70.02.32.32.30.0
    Africa subtotal301271/3059.19.63.61.05.22.34.01.35.62.75.31.03.31.33.71.3
Asia
    Bhattarakosol PJ Med Assoc Thai (2002)ThailandBiopsiesMY09/11270/2733.30.00.03.70.0
    Chan PKSJ Med Virol (1999)ChinaCellsMY09/11510/5164.721.67.80.00.02.05.90.015.72.09.80.02.00.00.00.0
    Chan PKSJ Med Virol (1999)ChinaCellsMY09/11510/5164.721.67.80.00.02.05.90.015.72.09.80.02.00.00.00.0
    Cho NHAm J Obstet Gynecol (2003)KoreaCellsGP5+/6+150150/073.326.71.35.36.02.70.710.00.77.34.00.70.02.01.3
    Hwang TSGynecol Oncol (2003)KoreaCellsGP5+/6+240/2470.816.70.04.24.24.24.20.00.016.78.40.00.04.20.0
    Asia subtotal252150/10267.121.82.74.00.04.93.62.210.20.87.13.60.80.01.80.9
Europe
    Astori GVirus Res (1997)ItalyCellsMY09/11111111/077.524.35.40.07.20.90.00.07.210.85.40.90.00.91.80.0
    Baay MFDEur J Gynaecol Oncol (2001)BelgiumBiopsiesGP5+/6+580/5869.024.11.73.45.21.71.70.00.019.00.00.00.00.05.2
    Cuschieri KSJ Clin Pathol (2004)United KingdomCellsGP5+/6+243243/090.928.012.817.39.912.311.95.00.09.59.17.48.62.15.3
    Cuzick JBr J Cancer (1999)United KingdomCellsMY09/11500/5042.012.00.02.04.012.02.010.02.00.0
    Giannoudis AInt J Cancer (1999)United KingdomBiopsiesGP5+/6+118118/0100.012.75.17.65.911.97.615.37.60.80.82.514.42.5
    Grce MEur J Epidemiol (1997)CroatiaCellsMY09/11183183/035.56.08.72.21.6
    Grce MAnticancer Res (2001)CroatiaCellsMY09/111,0281,028/054.511.65.82.93.1
    Humbey OEur J Obstet Gynecol Reprod Biol (2002)FranceCellsMY09/114040/060.030.05.05.07.52.510.07.52.52.5
    Kalantari MHum Pathol (1997)SwedenCellsMY09/111410/14170.917.75.712.15.0
    Labropoulou VSex Transm Dis (1997)GreeceBiopsies/cellsMY09/11510/5190.211.89.80.02.02.011.811.89.8
    Laconi SPathologica (2000)ItalyBiopsiesGP5+/6+200/2095.030.00.020.00.00.00.010.00.00.00.00.0
    Medeiros RInt Meet Gynecol Oncol (1997)PortugalBiopsiesMY09/11310/3174.235.53.20.0
    Meyer TInt J Gynecol Cancer (2001)GermanyBiopsies/cellsMY09/11130130/069.213.113.13.12.30.83.13.85.43.12.31.55.40.03.10.8
    Nindl IJ Clin Pathol (1999)GermanyCellsGP5+/6+490/4953.112.22.04.14.10.02.08.20.02.06.10.00.04.1
    Reesink-Peters NEur J Obstet Gynecol Reprod Biol (2001)NetherlandsCellsSPF10350/3597.128.631.411.431.417.1
    Southern SHum Pathol (2001)United KingdomBiopsiesGP5+/6+490/49100.010.22.04.12.06.16.110.224.58.24.12.00.00.00.0
    Tachezy RJ Med Virol (1999)Czech RepublicCellsMY09/118787/052.934.52.31.12.30.01.10.05.74.60.02.30.02.31.1
    Venturoli SJ Clin Virol (2002)ItalyCellsMY09/114040/047.57.510.05.02.52.50.0
    Voglino GPathologica (2000)ItalyBiopsiesMY09/111,4990/1,49973.024.715.94.28.94.3
    Zehbe IVirchows Arch (1996)SwedenBiopsiesGP5+/6+450/4593.340.011.16.72.26.76.76.72.22.20.0
    Zerbini MJ Clin Pathol (2001)ItalyCellsMY09/114343/053.514.04.79.30.09.32.3
    Europe subtotal4,0512,023/2,02867.819.410.46.93.74.85.46.05.76.85.13.45.73.03.82.5
North America
    Adam EAm J Obstet Gynecol (2000)United StatesCellsMY09/111610/16172.745.33.123.66.217.4
    ASCUS-LSIL Triage Study GroupAm J Obstet Gynecol (2003)United StatesCellsPGMY09/111,2421,242/092.421.59.016.111.112.811.710.97.66.810.511.04.410.07.06.0
    Brown DRSex Transm Dis (2002)United StatesCellsMY09/112525/088.040.012.04.04.020.012.024.04.04.00.08.04.08.012.00.0
    Evans MFMod Pathol (2002)United StatesBiopsiesGP5+/6+260/28100.07.17.110.70.03.67.110.70.07.13.610.73.610.73.63.6
    Jarboe EAHum Pathol (2004)United StatesCellsPGMY09/11950/9555.87.43.24.28.43.29.55.32.12.13.21.10.010.52.15.3
    Kulasingam SJAMA (2002)United StatesCellsMY09/11166166/079.015.73.615.011.47.28.49.05.410.23.67.83.03.64.22.4
    Liaw KJ Natl Cancer Inst (1999)United StatesCellsMY09/11173173/042.27.54.06.44.64.61.71.23.51.72.91.70.01.71.2
    Richardson HCancer Epidemiol Biomarkers Prev (2003)CanadaCellsMY09/114444/088.618.22.318.218.220.54.59.16.80.09.16.80.02.32.30.0
    Schiff MAm J Epidemiol (2000)United StatesCellsMY09/111900/19058.45.88.94.210.57.44.76.810.54.24.77.44.26.31.14.7
    Sellors JWCMAJ (2000)CanadaCellsMY09/112222/090.950.04.50.00.04.50.00.04.54.54.50.00.00.00.0
    Sellors JWCMAJ (2000)CanadaCellsMY09/112424/095.837.512.50.00.00.00.04.24.225.00.04.20.00.00.0
    Tortolero-LunaCad Saude Publica (1998)United StatesCellsMY09/11175175/064.612.66.98.04.09.1
    Tran-Thanh DAm J Obstet Gynecol (2003)CanadaBiopsiesMY09/11800/8083.815.08.83.88.815.08.08.86.36.38.87.55.03.80.01.3
    North America subtotal2,4251,872/55480.219.47.412.610.110.79.39.36.86.39.28.83.97.65.85.0
South/Central America
    Abba MCRev Argent Microbiol (2003)ArgentinaCellsMY09/11279279/080.326.52.50.722.92.55.4
    Ferrera AInt J Cancer (1999)HondurasCellsMY09/11440/4447.711.411.40.04.50.00.00.02.30.06.80.00.00.00.02.3
    Franco EPan Am J Public Health (1999)BrazilCellsMY09/112727/081.526.011.014.814.83.711.10.011.10.00.03.73.73.73.70.0
    Giuliano ACancer Epidemiol Biomarkers Prev (2001)Mexico (some United States)CellsPGMY09/114040/062.515.00.07.52.55.07.55.05.02.52.510.00.07.52.52.5
    Gonzalez-Losa MdRJ Clin Virol (2004)MexicoBiopsiesMY09/11104104/028.85.82.91.92.91.01.91.96.73.83.81.01.01.90.01.0
    Herrero RJ Natl Cancer Inst (2000)Costa RicaCellsMY09/11181181/073.012.27.29.96.18.87.24.48.86.14.46.61.11.72.23.9
    Illades-Aguiar BInt Papillomarivus Conf Proc (2001)MexicoBiopsiesMY09/111480/14886.512.82.00.00.70.00.70.03.42.00.70.036.50.00.74.1
    Lorenzato FInt J Gynecol Cancer (2000)BrazilCellsMY09/11620/6267.719.422.60.06.50.03.211.34.80.0
    Molano JBr J Cancer (2002)ColombiaCellsGP5+/6+7070/055.710.04.34.34.37.11.45.72.97.14.38.60.02.94.3
    Rattray CJ Infect Dis (1996)JamaicaCellsMY09/116262/080.69.78.14.84.812.98.116.1
    Strickler HJ Med Virol (1999)JamaicaCellsMY09/11186186/054.34.31.61.62.71.62.72.22.22.22.71.61.60.52.20.5
    Tonon SAInfect Dis Obstet Gynecol (1999)Argentina/ParaguayCellsGP5+/6+5555/096.474.55.512.7
    Torroella-Kouri MGynecol Oncol (1998)MexicoBiopsies/cellsMY09/112121/033.34.80.04.80.04.80.00.00.00.00.00.00.00.00.04.8
    South/Central America subtotal1,2791,025/25468.316.74.83.33.63.33.62.15.27.43.62.97.91.22.23.3
Total 8,308 5,341/2,967 71.218.78.28.07.67.26.76.56.36.26.15.85.34.64.33.7
  • * HPV prevalence represents that at study enrollment and not at LSIL diagnosis.