Table 5.

Risk estimates for follicular lymphoma associated with cigarette smoking in the pooled study population by smoking history

Smoking exposureCurrent smokers
Former smokers
Controls/casesOR (95% CI)Controls/casesOR (95% CI)
Years since quit
    1-10876/1601.16 (0.95-1.41)
    11-20739/1441.12 (0.91-1.38)
    21-30586/930.90 (0.70-1.15)
    ≥31645/830.98 (0.76-1.28)
    P for linear trend0.03
Intensity
    1-10639/831.16 (0.90-1.50)982/1711.10 (0.91-1.33)
    11-20901/1561.45 (1.18-1.77)1,006/1681.13 (0.93-1.36)
    21-30276/531.41 (1.02-1.95)311/641.28 (0.96-1.72)
    ≥31161/261.14 (0.73-1.77)406/530.86 (0.63-1.17)
    P for linear trend0.670.30
Duration
    1-10229/110.51 (0.27-0.96)756/1200.97 (0.78-1.21)
    11-20370/411.11 (0.77-1.59)715/1401.16 (0.94-1.43)
    21-35657/1371.48 (1.18-1.84)870/1541.08 (0.88-1.32)
    ≥36840/1581.38 (1.12-1.70)509/761.09 (0.83-1.43)
    P for linear trend0.200.34
Pack-years
    1-10514/591.08 (0.80-1.45)1,093/1911.10 (0.92-1.32)
    11-20404/571.27 (0.94-1.73)515/891.10 (0.85-1.41)
    21-35465/821.43 (1.09-1.86)480/791.07 (0.82-1.39)
    ≥36591/1191.45 (1.15-1.82)603/971.13 (0.88-1.44)
    P for linear trend0.850.63
  • NOTE: Reference group = nonsmokers (n = 3,914 controls, n = 612 follicular lymphoma cases). ORs and 95% CIs were estimated using joint fixed-effects logistic regression models, adjusted for study center, age, sex, and race. P for linear trend among smokers only (excludes nonsmokers).