Table 2.

Partial Spearman correlation coefficients between C-peptide, IGF-I, IGFBP-1 and -3, glycosylated hemoglobin, and other variables among colorectal cancer controls nested in Nurses' Health Study, 1989-2000

C-peptideIGFBP-1IGF-IIGFBP-3RatioHbA1cBMIAlcoholPhysical activity
C-peptide1.00
IGFBP-1−0.53*1.00
IGF-I0.07−0.29*1.00
IGFBP-30.13−0.150.58*1.00
Ratio−0.005−0.27*0.81*0.071.00
HbA1c0.20−0.180.150.150.091.00
BMI0.44*−0.43*−0.030.03−0.040.141.00
Alcohol−0.070.07−0.090.02−0.11−0.008−0.161.00
Physical activity−0.080.050.050.14−0.080.002−0.120.141.00
  • NOTE: Adjusted for age, assay batch, and time since last meal.

  • * P < 0.05.

  • P < 0.01.

  • P < 0.001.