Table 2.

Total NNAL, 1-HOP, and total cotinine in the urine of smokers of regular, light, and ultralight cigarettes, per mg creatinine

nMean (95% CI)
Total NNAL (pmol/mg creatinine)1-HOP (pmol/mg creatinine)Total cotinine (pmol/mg creatinine)
Study 1
    Regular232.11 (1.76-2.46)1.94 (1.45-2.44)28.2 (21.8-34.6)
    Light582.21 (1.93-2.48)1.41 (1.15-1.66)25.2 (22.2-28.0)
    Ultralight342.42 (1.97-2.88)1.58 (1.24-1.92)27.0 (22.0-32.1)
Study 2
    Regular243.23 (2.45-4.13)1.53 (1.13-1.93)25.8 (22.5-29.0)
    Light222.65 (2.10-3.20)1.62 (1.03-2.22)28.2 (23.0-33.5)
    Ultralight142.33 (1.36-3.31)1.40 (0.84-1.96)21.9 (14.2-29.6)
Pooled*
    Regular472.68 (2.22-3.14)1.73 (1.42-2.05)27.0 (23.4-30.5)
    Light802.33 (2.08-2.58)1.47 (1.22-1.71)26.0 (23.4-28.6)
    Ultralight482.40 (1.97-2.82)1.53 (1.24-1.81)25.5 (21.3-29.8)
  • * Ps: regular versus light, NNAL 0.50, 1-HOP 0.56, cotinine 1.0; regular versus ultralight, NNAL 0.94, 1-HOP 1.0, cotinine 1.0; light versus ultralight, 1.0 for all measures.