Table 1.

Patient details

ControlsNo SIMBarrett's esophagusEsophageal adenocarcinoma
No.6495024
Mean age (range)52 (28-83)53 (32-69)63 (30-82)70 (58-86)
Sex (M/F)36:28*7:234:1620:4
Current reflux symptoms21 (33)2 (22)15 (30)5 (21)
Previous reflux symptoms42 (66)8 (89)50 (100)21 (88)
Nocturnal reflux (%)22 (34)5 (56)37 (74)9 (38)
Duration of reflux (median years, range)3 (1-26)5.5 (4-20)10 (1-50)10 (1-50)
Hiatus hernia5 (8)1 (11)22 (44)NI
Esophagitis9 (14)1 (11)6 (12)NI
Ever smoking32 (50)2 (22)25 (50)13 (54)
Alcohol48 (75)7 (78)38 (76)16 (67)
NSAID/aspirin11 (17)1 (11)8 (16)6 (25)
Current PPI use26 (41)9 (100)42 (84)16 (67)
  • NOTE: Data shown are no. individuals (%) unless otherwise indicated.

    Abbreviation: NI, no information.

  • * P < 0.05 compared to esophagus adenocarcinoma.

  • P < 0.05 compared to Barrett's esophagus and esophageal adenocarcinoma.

  • P < 0.001 compared to Barrett's esophagus.