Cytology | PreTect HPV-Proofer | PreTect HPV-Proofer | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|

Positive | Negative | Positive | Negative | |||||||||||

Normal (n = 3,970) | ||||||||||||||

Gp5+/6+ PCR | Positive | 68 | 300 | TS-PCR | Positive | 71 | 73 | |||||||

P < 0.000 | Negative | 27 | 3,575 | P < 0.000 | Negative | 24 | 3,802 | |||||||

Unsatisfactory (n = 64) | ||||||||||||||

Gp5+/6+ PCR | Positive | 0 | 3 | TS-PCR | Positive | 0 | 2 | |||||||

P = 0.083 | Negative | 0 | 61 | P = 0.157 | Negative | 0 | 62 | |||||||

ASCUS (n = 57) | ||||||||||||||

Gp5+/6+ PCR | Positive | 11 | 16 | TS-PCR | Positive | 11 | 3 | |||||||

P < 0.000 | Negative | 1 | 29 | P = 0.317 | Negative | 1 | 42 | |||||||

LSIL (n = 20) | ||||||||||||||

Gp5+/6+ PCR | Positive | 6 | 9 | TS-PCR | Positive | 6 | 4 | |||||||

P = 0.003 | Negative | 0 | 5 | P = 0.046 | Negative | 0 | 10 | |||||||

HSIL (n = 25) | ||||||||||||||

Gp5+/6+ PCR | Positive | 13 | 3 | TS-PCR | Positive | 13 | 0 | |||||||

P = 0.083 | Negative | 0 | 9 | P = 1 | Negative | 0 | 12 | |||||||

Total (n = 4,136) | ||||||||||||||

Gp5+/6+ PCR | Positive | 98 | 331 | TS-PCR | Positive | 101 | 82 | |||||||

P < 0.000 | Negative | 28 | 3,679 | P < 0.000 | Negative | 25 | 3,928 |

NOTE: PreTect HPV-Proofer and type-specific PCR detects HPV types 16, 18, 31, 33, and 45. Type-specific PCR was done on Gp5+/6+ consensus PCR–positive samples. The probability calculus was done using McNemar's test.

Abbreviation: TS-PCR, type-specific PCR.