Table 2.

Number of HPV positive samples detected by PreTect HPV-Proofer and PCR

CytologyPreTect HPV-Proofer
PreTect HPV-Proofer
PositiveNegativePositiveNegative
Normal (n = 3,970)
    Gp5+/6+ PCRPositive68300TS-PCRPositive7173
    P < 0.000Negative273,575P < 0.000Negative243,802
Unsatisfactory (n = 64)
    Gp5+/6+ PCRPositive03TS-PCRPositive02
    P = 0.083Negative061P = 0.157Negative062
ASCUS (n = 57)
    Gp5+/6+ PCRPositive1116TS-PCRPositive113
    P < 0.000Negative129P = 0.317Negative142
LSIL (n = 20)
    Gp5+/6+ PCRPositive69TS-PCRPositive64
    P = 0.003Negative05P = 0.046Negative010
HSIL (n = 25)
    Gp5+/6+ PCRPositive133TS-PCRPositive130
    P = 0.083Negative09P = 1Negative012
Total (n = 4,136)
    Gp5+/6+ PCRPositive98331TS-PCRPositive10182
    P < 0.000Negative283,679P < 0.000Negative253,928
  • NOTE: PreTect HPV-Proofer and type-specific PCR detects HPV types 16, 18, 31, 33, and 45. Type-specific PCR was done on Gp5+/6+ consensus PCR–positive samples. The probability calculus was done using McNemar's test.

    Abbreviation: TS-PCR, type-specific PCR.