Table 6.

Sensitivity, specificity, PPV, and NPV for PreTect HPV-Proofer and consensus PCR on cytological HSIL and histological CIN2+ samples

All cytology (n = 4,136), end-point cytological HSIL (n = 25), %
Cytological HSIL (n = 23), end-point histological CIN2+ (n = 14), %
PreTect HPV-ProoferGp5+/6+ PCRPreTect HPV-ProoferGp5+/6+ PCR
Sensitivity52.064.085.792.9
Specificity97.3*90.088.966.7
PPV10.33.792.381.3
NPV99.799.880.085.7
  • NOTE: Women with cytological HSIL have been followed-up by histology.

    Abbreviations: PPV, positive predicted value; NPV, negative predicted value.

  • * Significant different according to nonoverlapping 95% confidential intervals (data not shown).