Table 1.

NCOA3 associated to the polyglutamine repeat lengths in NCOA3 in familial breast cancer

GroupGln repeatsCases (%)Controls (%)OR (95% confidence interval)P
Polish 646 samples1 allele <2866 (18.7)59 (20.1)0.87 (0.56-1.34)0.507
28/28, 28/29, 28/30184 (52.1)143 (48.8)1.00
2 alleles ≥29103 (29.2)91 (31.1)0.88 (0.61-1.28)0.481
German 481 samples1 allele <2868 (28.6)56 (23.0)1.25 (0.79-1.98)0.324
28/28, 28/29, 28/30113 (47.5)116 (47.7)1.00
2 alleles ≥2957 (23.9)71 (29.2)0.82 (0.52-1.30)0.383
Combined 1,127 samples1 allele <28134 (22.7)115 (21.5)1.03 (0.75-1.41)*0.905
28/28, 28/29, 28/30297 (49.8)259 (48.8)1.00
2 alleles ≥29160 (27.1)162 (30.2)0.86 (0.64-1.14)*0.304
  • * Mantel-Haenszel adjustment.