Table 2.

ORs and 95% CIs for the joint effects of COX2 genotype and NSAID use on breast cancer (invasive and carcinoma in situ) among African American women, the Carolina Breast Cancer Study

NSAID use categoryCOX2 genotype
Ala/Ala or Val/AlaVal/Val
Cases (n)/controls (n)OR* (95% CI)Cases (n)/controls (n)OR* (95% CI)
Never1/20.2 (0.0-2.3)54/151.0 (reference)
Occasional27/110.7 (0.3-1.9)189/1840.3 (0.1-0.5)
Regular18/170.3 (0.1-0.9)173/1380.3 (0.2-0.6)
  • * Adjusted for age and offset term used to oversample younger women and African American women.